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phenobarbital will lower the level or outcome of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Powerful or reasonable CYP3A4 inducers may raise level of diazepam elimination; as a result, efficacy of diazepam may very well be decreased.Routine Forming. Phenobarbital could be habit forming. Tolerance an